The Drug Enforcement Administration plans to hold a drug take-back event from 10 a.m. to 2 p.m. April 27 at the O'Brien Water Reclamation Plant, 3500 Howard St., just across Howard Street in Skokie. The collection is part of "National Prescription Drug Take Back Day." Most abused prescription drugs come from family and friends, and unused or expired prescription medications can lead to accidental poisoning, overdose and abuse.