O'Connor and Napolitano will debate between 7 and 8 p.m. Wednesday on WTTW's Chicago Tonight.
O'Connor, who is seeking a second term on the City Council, won won 47.7 percent of the vote on Feb. 24 and Napolitano won 42.5 percent. Hardware store owner Joe Lomanto, who won 9.7 percent of the ballots, declined to endorse either candidate.
The 41st Ward includes parts of Norwood Park, Edison Park, O'Hare and Edgebrook.
For more neighborhood news, listen to DNAinfo Radio here: