One lane of the Harlem River Drive will be closed as safety equipment is installed on the High Bridge.
Both Manhattan-bound lanes on the Brooklyn Bridge will be closed this weekend and next.
Construction on the Park Avenue tunnel will prompt overnight northbound lane closures for several days.
A crash on the LIE near Francis Lewis Boulevard closed several lanes on the highway Wednesday.
Multiple road and tunnel projects will affect commuters in Manhattan for several days starting Saturday.
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