The suspects, both described as between 25 and 35, forced their way into an apartment near Sedgwick Avenue and West 195th Street about 3:15 p.m., police said.
Once inside, they held up a 44-year-old man as they removed his wallet, then fled the building.
No injuries were reported.
One suspect was described as 5 feet 7 inches tall and 155 pounds, last seen wearing a dark-hooded sweatshirt. The other was described as 5 feet 9 inches tall and 170 pounds, last seen wearing a red or pink T-shirt.
Anyone with information about the incident is asked to call the NYPD's Crime Stoppers hotline at 800-577-TIPS (8477). Members of the public can also submit tips through the Crime Stoppers website by texting tips to CRIMES (274637), then entering TIP577.