There were also delays on J and M lines and on southbound 4 and 6 trains on Tuesday morning.
Service on the F, R, M and E lines were disrupted Tuesday evening.
Trains along several subway lines were disrupted because of a power outage, officials said.
B and D trains were rerouted because of a broken rail at Grand Street, accoridng to the MTA.
The 2, 3, 4, 5, 6, 7, A, C, D, F, J, M, N, Q lines and the 42nd Street shuttle will all be disrupted.
The 1, 2, 3, 4, 5, 6, 7, A, C, D, E, F, G, J, M and S lines will have changes.
The 2, 3, 4, 5, 6, A, E, F, G, J, M, N, Q and R lines are all slated to undergo service changes.
No criminality is suspected, officials said.
A man was hit and killed by a Forest Hills-bound R train in the Grand Ave.-Newtown Station: officials.
The change is to meet ridership demand, which is at an all-time high, according to the MTA.
The 2, 3, 4, 5, 6, A, C, E, F, G, J, M, N, Q, R and S lines will be affected this weekend.
The delivery was made in December and included the rail involved with last week's derailment.
Four injured people were taken to hospitals while local service was restored for evening rush, MTA said.
Upgrades and maintenance is scheduled across 15 subway lines late Friday until early Monday.
Work will affect the 2, 3, 4, 5, 6, 7, A, E, F, G, J, M, Q and two shuttle lines, the MTA said.
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