Shu Fan Haung, 82, died from her injuries after she was hit while crossing South Street last week.
The city's 23 cameras have recorded 183,000 violations since January, officials said.
The new plaza is also meant to help reduce traffic-related injuries and deaths.
The changes are expected to lessen dangerous turns and reduce speeding, the DOT said.
The signing took place near the Woodside intersection where an 8-year-old was killed in December.
Politicians lauded the new service, but advocates for the disabled said more could be done to help them.
The DOT made $300,000 worth in infrastructure changes to the intersection to make it safer.
The Staten Island Ferry will run every half-hour through weekend nights, instead of every hour.
A woman was hit by a BxM18 bus less than one block from the site of DOT's slow zone press conference.
The initiative will knock down the speed limit from 30 to 25 mph on Northern Blvd.
The 8.3-mile stretch of Broadway will become New York's fourth arterial slow zone this July.
The speed limit on a 7.6-mile stretch of Atlantic Avenue will be reduced from 30 to 25 mph.
The proposed law comes as visually impaired pedestrians demand a seat at the table.
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