The prince's Harlem visit follows a look at Sandy-stricken areas of New Jersey Monday. He'll wrap-up his tour with a polo match at the Greenwich Polo Club in Connecticut on Wednesday, CBS New York reported.
Exact details of his itinerary are under wraps because of security concerns. He is expected to arrive in the city Monday evening.
The prince comes to New York after a weekend visit to Colorado, where he joined Olympic swimming champion Missy Franklin in opening the 2013 Warrior Games for wounded veterans.
His Harlem appointment comes a day after a Big Apple visit by President Barack Obama.
The dignitaries' visits were expected to snarl traffic across Manhattan.